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Principal Scientist – Preclinical & Translational Research
At Rejuvenate Bio, we aspire to treat aging and age-related diseases. We are a spinout from George Church's lab at Harvard Medical School and the Wyss Institute. Our goal is to treat pets and people with targeted gene therapies aimed at curing specific disease states associated with old age that can potentially extend overall health and maximize lifespan.
Duties & Responsibilities
Rejuvenate Bio is looking for a highly motivated individual to join our energetic team and accelerate the development of our therapies. The Principal Scientist position will directly support efforts to drive forward our future commercial offerings. Gene therapy is at a tipping point. We have already seen remarkable strides toward curing untreatable diseases. They will be responsible for independently investigating new therapeutics for treating aging and age-related diseases, supporting our current programs, and managing RAs. The role reports to the Sr. Director of Preclinical Development of Rejuvenate Bio.
Responsibilities will include:
- Executing experiments on the bench, extensive literature review, and overseeing product candidate development from proof of concept to IND submission.
- Contribute to in vivo study protocol and report writing, data packages for regulatory submissions, scientific manuscripts, and internal and external presentations.
- Effectively collaborate across CMC, regulatory and clinical groups to devise and execute a biomarker plan ad coordinate related activities and timelines to ensure seamless pre/clinical studies execution.
- Accountable for on-time, high-quality results and communicating progress.
- Monitoring ongoing experiments and suggesting alternatives or solutions.
- Managing a small team of Research Associates.
- Following laboratory protocols and safety regulations.
- Strong work ethic, communication skills, and goal-oriented personality.
- Perform all other duties as assigned by supervisor or manager.
Basic Qualifications:
- Ph.D. in immunology, cell biology, biochemistry, or related field required
- 5+ years of industry experience.
- Experience with AAV and other standard microbial techniques (e.g., ELISA, qPCR, cloning, western blot, cell culture, etc.).
- Experience with IND-enabling studies, CRO relationships, and project management.
- Strong immunology background and familiarity with AAV gene therapy's immunogenicity aspects for regulatory filings.
- Experience managing a team of people and working with different groups. Proven ability to define a project goal and work independently or in a group setting to achieve it.
- Performing detailed and accurate documentation of all experiments and laboratory practices.
- Excellent verbal and written communication skills.
- Advanced planning, organization, and time management skills, including supporting and prioritizing multiple projects.
- Familiar knowledge of GLP and GMP requirements about protein and gene therapy process development and Quality Control (QC) testing preferred.
- Advanced knowledge of Excel, Word, PowerPoint, and other associated software used in the scientific field.
If interested, email jobs@rejuvenatebio.com with a resume and cover letter. We are located in San Dieg,o California.
EEO Statement:
Rejuvenate Bio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Rejuvenate Bio is an E-Verify Employer in the United States.